Showing posts with label HCG. Show all posts
Showing posts with label HCG. Show all posts

Sunday, December 11, 2016

Update - Part 1

It has been a month since my transfer and boy, has it been a whirlwind!

My transfer (on Thursday, 11/10/16) went well. I went to my acupuncture appointment beforehand, suffered through the discomfort of a full bladder during the transfer, went to my follow up acupuncture appointment, and then went home and rested. While I took things pretty easy last time, I was even more "lazy" this time around and stayed in bed (or lied on the couch) for essentially the entire time I was at home (Thursday-Monday). I even switched my flight to a day later to give myself an extra day. I ate pineapple core, walnuts and Brazil nuts, drank pomegranate juice, and kept my feet warm. I was extra careful to sleep on my back only, and then eventually started sleeping on my sides as well. 
Embryo (5 days)


On Tuesday, 11/15/16, I flew back home. David met me at the airport, and as soon as we got my luggage, we hopped in the car and stopped in a random parking lot so he could give me my Progesterone injection. The next day, I went back to work. I had 2 days of work that week, and thankfully, only 1 the next (since it was the week of Thanksgiving). I tried to use automatic doors and take the elevator as much as I possibly could. We spent Thanksgiving with friends, but other than that, I laid low and tried to use as little energy/strength as possible.

I had every intention of not doing a HPT, but on the evening of Friday, 11/18/16 (8dp5dt), David (forgot) and playfully smacked me on my butt, which immediately made me start freaking out. I gave in to my anxieties and took a cheap dollar store test, fully expecting it to be negative...except a faint second line finally appeared after the full 5 minute wait! At first, I thought it was a phantom line, and I read and re-read the instructions. After the wait time, it was clear that while light, there was definitely a second line! I called him into the bathroom and asked him what he saw. I think his reply was something like, "I'm going to be very cautious before believing anything." All the anxieties, fear, and worry, immediately rushed away. I could not believe it!

The next day, and the next day, and the next day, I took several more dollar store tests. I checked to see if the second line was still there and if it was getting darker. I even splurged and got a First Response Early Result test, and the second line was darker than the control line.

What was so weird was that during my 2ww, I did not have many symptoms at all, if any. The first transfer, I had headaches, cramping, heartburn, nausea...this time around, I had a couple headaches that I attributed to the injections...but a few days before taking the HPT, I remember sleeping with my hands on my abdomen, and I felt pregnant. Of course, I dismissed the idea, since I didn't know what it felt like to be pregnant. 

Finding out I was pregnant was the most amazing feeling in the world, but it sucked because the only person I could share it with was David. We didn't want to share it with anyone else until I had passed all my beta tests and possibly even heard the heartbeat. My first beta was scheduled for the day before Thanksgiving, so we thought it would be perfect to tell my parents (who were visiting my brother) on Thanksgiving day. I was so nervous on the day of the beta (11/23/16), but was so excited when my nurse called me. She said, "Congratulations. You're pregnant!" and told me that my HCG level was at 665.7, which was higher than I had expected. My second beta was scheduled for the day after Thanksgiving, 11/25/16, and the number rose to 1,690. The third was that following Monday, 11/28/16, and it was 6,013!

I thought that getting a positive on a HPT would make everything super easy from there on out, but I was so wrong. With IVF, you are faced with so many hurdles during the entire process, and no sooner do you make it over one, that you are faced with ten more. The doctor wants to see your betas rise (preferably by 65%) with each test. After that, you are scheduled for ultrasounds at 6-7 weeks and then again at 8-9 weeks. He expects to see major milestones in development such as a fetal pole and yolk sac, and a heartbeat, before he is comfortable enough to release you into the care of your OBGYN. After each of these tests, I would be relieved to receive good results, but then start worrying about what would happen next. 

To be continued...

Tuesday, July 26, 2016

Preparing for the Worst

I hate these things! (And they are so expensive!)
My beta is tomorrow morning at 10:30am and I am preparing for the worst.

 I ended up taking HPTs on Days 6, 8, 9, 10, and 12. All negative. I started getting worried on Day 8, and the rest of my hope disseminated with each test I took. It was like letting air out of a balloon. HPTs are the devil.

I have to say that perusing message boards at this time was not helpful, especially when other women, who had transfers on or around the same day as me, were starting to see faint positive lines on their tests. I would say probably 90% of the messages I read of people with successful betas had seen positive lines by Days 5-9 or were those who never did HPTs at home. I had pretty much succumbed to defeat until I spoke to my friend Anna online last night. She started the IVF process a month ahead of me (and did a fresh transfer) and is now at the beginning of her 2nd trimester with a baby girl. She told me she did not get a positive until the morning of her beta (Day 14). That did give me a faint glimmer of hope, but the cheap dollar store HPT I took today (Day 12) was clearly negative, so that quickly went out the door.

Part of me is still praying for a miracle, but I know I should not get my hopes up or count on anything positive coming out of tomorrow. I'm dreading the phone call tomorrow afternoon because I know it will be the last nail in the coffin. And let me tell you, each of the negatives on these tests killed me a little bit. You build up so much anxiety and hope to see the faintest of lines because maybe, just maybe today your body has made enough HCG to detect, and even just a faint line is enough to give you some sort of relief...and of course, that positive line would of course provide that relief...but no line means the exact opposite of relief. It's devastation. It's getting the wind knocked out of you. It's having your heart wrenched out of your chest. It's your world crashing down. It's the worst stomachache in the world. It's absolutely the worst feeling in the world, and nobody else could ever possibly understand it unless they've been in your exact shoes. 

I just devoted 4 months (and my entire summer vacation) to this, the countless injections, the hormones, the pain, the dietary restrictions, the physical restrictions, the mental anguish, the loss, the mourning, the money, putting all my eggs (literally) into 1 basket...and to watch it succumb to nothing.

My biggest frustration is we have to start all over again. We only had the 1 normal embryo (and 1 that is currently being re-tested)...so unless the last embryo is normal, we will have to go through STIMS once again, and then more testing, and then another FET...and the next time I will have 4 months to devote to this is next summer, a year from now. Right now I do not know how I can possibly get through teaching another 2 semesters before we can try again. This does not even seem feasible to me. I do not have the energy, strength, or capability to even think about prepping 4 classes which start in less than a month. 

One thing I've learned from this FET cycle is that HPTs are a bad idea. I do not recommend them to anyone. The best case scenario is that you see a positive at some point and your joy comes sooner than your beta. The worst case scenario is that your hope is crushed a little bit each time you test, and then crushed completely on beta day. I think that having it crushed just one time would be so much better than 6 times. I can't promise I wouldn't do them again next time, but I do know I wish I hadn't done them this time.

The beta is in 10.5 hours. Praying for the best; preparing for the worst.


Thursday, May 26, 2016

Day 7 of Stims

Top: Gonal-f
Bottom: Cetrotide in its "Lunchables" pack
Update
I started stims on Friday (5/20/16), had a check up on Monday (5/23/16), and again yesterday (5/25/16). On Monday, during the u/s, the sonographer found 9 follicles in my right ovary and 10 in my left, and was able to measure a number of them that were 10+ mm. That afternoon, my nurse called and told me that they were surprised to see how quickly I was progressing (she assured me this was "a good problem to have") and that the doctor wanted to dial back on my Gonal-f (from 175 IU to 150 IU), to increase my Menopur (from 75 IU to 150 IU) and to add in a morning injection of Cetrotide (0.25 mg). My estrogen (estradiol) level was at 109 pg/ml. Yesterday, the u/s showed that more follicles were enlarging, and when my nurse called she said that my estrogen level was now at 781 pg/ml. My next appointment is tomorrow (Friday, 5/27/16).
Stims: Day 6 - 2nd morning of Cetrotide (25 mg),
5 nights of Gonal-f (175-150 IU) & Menopur (75-150 IU)
Starting Cetrotide
I was a little nervous to inject the Cetrotide, as I've heard it also burns and can cause an itchy rash at the injection site, but I found it to be pretty unremarkable. It is refrigerated, and comes in its own little "Lunchables" style pack, with syringe pre-filled with sterile water, powder vial, and alcohol swabs--I like how convenient this is. My only problem with it is getting all of the powdered medicine to dissolve completely. The injection itself didn't burn for me and only itched a tiny bit the first day, but nothing like a mosquito bite or anything. I did bruise at the first injection site. This morning when I did the injection, I accidentally stabbed my middle finger as the needle bent and went through the cap. I'm not sure if it was the throbbing pain in my finger or the medicine, but I got super nauseated and dizzy, and it was all I could do to rifle through my parents' bathroom drawers to find some Neosporin before I passed out. Luckily, I just barely made it to my bed before falling over. It was a rough morning.

The trigger
I got some good news from my nurse. I have been a little anxious about my upcoming trigger injection, as most of what I've read has stated that they need to be injected intramuscularly (i.e., in the butt muscle). We were prepared to hire a nurse who would be on call for 3 consecutive evenings (cost ~$125-$175) to come give me the injection, which could very well be in the middle of the night. My nurse told me that all my medications including the trigger injection will be given subcutaneously in my abdomen. She explained that there are 2 types of trigger injections: Lupron and HCG. "The reason why some physicians use one over the other is the mechanism of the trigger. For those patients who have a lot of follicles or are at risk for developing ovarian hyperstimulation syndrome (OHSS), you would use the Lupron, as this medication is in your system for a short amount of time. The HCG trigger is for the patient who will have an average response to the stimulation medication as the HCG medication is in the system longer." So I don't need to hire a nurse, and I can do the trigger injection myself!

Exercise
I was told I could continue my normal cardio and strength training during the early stages of injections (days 1-5), but by day 6, I would want to decrease the intensity and focus on non-impact exercises (yoga, light elliptical, swimming, etc.). Yesterday was day 6, so I took Noah for a 2 mile walk. Today I am going to do the same, but also hit the gym for a light elliptical workout (decreased intensity/time). I did an entire week's worth of cardio/strength from Saturday-Tuesday, so I was at least able to get that in...but it's going to kill me a little to not be able to do strength training as usual. Oh well...I'll live.
Mickey Collector's Series Band-Aids

Little treats
I've decided to reward myself after my nightly injections with a little treat: popsicles. I am loving these little Outshine Fruit Bars. They're only 35-45 calories a pop (ha!). I also got some Mickey Band-Aids, because who doesn't love Mickey? Little things like that, walking the dog, and working out, have helped keep me sane. I've been getting daily headaches which I am able to treat (for the most part) with Extra Strength Tylenol, lots of water, and naps...I've been taking lots and lots of naps!